Probiotics and Digestive Disorders: Can Good Bacteria Alleviate Symptoms

Probiotics and Digestive Disorders: Can Good Bacteria Alleviate Symptoms


6 minute read

Hello, all you health enthusiasts out there! Come join us for our exciting discussion today about digestive disorders and the amazing benefits of probiotics in easing pesky symptoms. Throughout our journey, we'll be diving into the following topics:

1. Introduction to Probiotics

2. Digestive Disorders and probiotics used to alleviate symptoms

3. How Probiotics Work: Balancing the Gut Ecosystem

Introduction to Probiotics: Understanding the Role of Good Bacteria

Role of good bacteria

Probiotics are living organisms, such as bacteria or fungi, that confer health benefits when consumed. They play a crucial role in adding beneficial bacteria to the body.

The primary sources of probiotics include genera like Lactobacillus, Bifidobacterium, Saccharomyces, Enterococcus, Streptococcus, Pediococcus, Leuconostoc, Bacillus, and Escherichia coli¹. Specific strains within these genera have demonstrated various health benefits.

The gut microbiota contributes significantly to enhancing resistance against infections, aiding in the differentiation of the host immune system, and synthesizing certain nutrients such as vitamins, short-chain fatty acids, and other low molecular mass molecules¹.

The presence of good bacteria in the gut is essential for several reasons. It helps in digesting food more efficiently, strengthens the immune system, keeps harmful bacteria in check, and plays a crucial role in keeping digestive disorders at bay.

Gut Microbiota's Role:

  • Enhances infection resistance.
  • Supports immune system differentiation.
  • Synthesizes vital nutrients.

Importance of Good Gut Bacteria:

  • Enhances digestion efficiency.
  • Strengthens the immune system.
  • Prevents digestive disorders.

Digestive Disorders and probiotics used to alleviate symptoms:

People who struggle with digestive disorders often face immense struggles, hindering their ability to carry out their daily tasks. These disorders can cause significant discomfort and pain, making it crucial to prioritize gut health.

Probiotics have been shown to be a highly effective means of addressing digestive problems. It is crucial to understand that choosing the appropriate probiotic should involve consulting with a healthcare professional.

While probiotics offer a natural remedy for managing digestive disorders, it is essential to select the right probiotic tailored to the specific issue. Each digestive disorder may require a different type of probiotic, underscoring the necessity of seeking professional guidance.

There are various digestive disorders on the rise due to dysbiosis of gut microbiota.

Among the frequently encountered digestive issues are antibiotic-associated diarrhea, Clostridium difficile colitis, infectious diarrhea, ulcerative colitis, Crohn’s disease, pouchitis, and irritable bowel syndrome².

 Rising Digestive Disorders:

  • Increasing cases due to gut microbiota dysbiosis.
  • Include antibiotic-associated diarrhea, Clostridium difficile colitis, infectious diarrhea, ulcerative colitis, Crohn’s disease, pouchitis, and irritable bowel syndrome².

Now, let's explore the impact these digestive disorders can have on your body and understand how incorporating probiotics into your routine can provide relief from symptoms.

Antibioticassociated diarrhea (AAD):

AAD is caused by disruption of the normal gut microbiota from antibiotic use, allowing pathogenicbacteria to proliferate2,3.Metaanalyses showed probiotics like S. boulardii3 and various Lactobacillus species significantly decreased the risk of AAD when taken alongside or after a course of antibiotics.

Clostridium difficile colitis (CDC):

CDC is another such digestive disorder that is caused when normal gut flora is disrupted causing overgrowth of C. difficile, usually after antibiotic use. S. boulardiiwhen taken with vancomycin has been shown to lower recurrence risk in one large trial2,4. Probiotics help reestablish competition against C. difficile in the gut microbiome keeping it under control.  

Infectious diarrhea:

It is an acute bacterial, viral or parasitic gut infection caused mainlyEscherichia coli, Shigella, Salmonella, Campylobacter ,Yersinia, and Clostridium spp.Meta Analysis found probiotics like Lactobacillus species shortened symptom duration by about 30 hours on average.Probiotics work by strengthening intestinal barrier integrity and competing with pathogenic microbes.

Irritable bowel syndrome (IBS):

IBS is a digestive disorder with multiple symptoms, including constipation, diarrhoea, and stomach pains. In two carefully planned randomized control trials, Bifidobacteriuminfantis 35624 has proven to be effective in alleviating symptoms without causing any negative side effects.

How Probiotics Work: Balancing the Gut Ecosystem

Balancing the Gut Ecosystem

Our gut is a diverse ecosystem containing microbes like bacteria or fungi. These microbes are present in the trillions. Though a healthy gut microbiota is essential to keep the body healthy, the gut also contains bad bacteria that could cause trouble when present in large numbers.

When you take in antibiotics, it destroys all the good and bad bacteria that come in its path. Thus, causing an imbalance in microbiota in the gut which could lead to a lot of digestive issues.

Here, probiotics come into play as allies for the good bacteria in your gut. Probiotics bring in large amounts of good bacteria into the gut, which can help restore the good bacteria population and bring back the microbiome balance.

Probiotics also bring in bacteria that colonize the gut lining making it a protective layer against harmful invaders. Probiotics help in increasing the number of good bacteria, which would keep the bad bacteria in check by competing with them for nutrients and space in the gut.

Going back to the original question, do probiotics help with digestive disorders? The answer is definitely yes, and this is supported by clinical research.

But added the right probiotic is taken to address the digestive disorder. It's essential to recognize that probiotics are not standalone cures for digestive disorders; their optimal results are achieved when combined with prebiotics, adopting healthy eating habits, and reducing alcohol consumption.

  • Gut houses trillions of microbes; balance is crucial.
  • Antibiotics disrupt this balance, leading to issues.
  • Probiotics act as allies, restoring balance and creating a protective gut lining.
  • Summary: Probiotics help with digestive disorders, but optimal results come with prebiotics, healthy habits, and reduced alcohol.

References:

1. Fijan S. Microorganisms with claimed probiotic properties: an overview of recent literature. Int J Environ Res Public Health. 2014 May 5;11(5):474567. doi: 10.3390/ijerph110504745. PMID: 24859749; PMCID: PMC4053917.

2. Verna EC, Lucak S. Use of probiotics in gastrointestinal disorders: what to recommend? TherapAdvGastroenterol. 2010 Sep;3(5):30719. doi: 10.1177/1756283X10373814. PMID: 21180611; PMCID: PMC3002586.

3. TanırBasaranoğlu S, Karaaslan A, Salı E, Çiftçi E, GayretliAydın ZG, AldemirKocabaş B, Kaya C, ŞenBayturan S, Kara SS, YılmazÇiftdoğan D, Çay Ü, GundogduAktürk H, Çelik M, Ozdemir H, Somer A, Diri T, Yazar AS, Sütçü M, Tezer H, KaradagOncel E, Kara M, Çelebi S, ÖzkayaParlakay A, Karakaşlılar S, Arısoy ES, Tanır G, Tural Kara T, Devrim İ, Erat T, Aykaç K, Kaba Ö, Güven Ş, Yeşil E, TekinYılmaz A, YaşarDurmuş S, Çağlar İ, Günay F, Özen M, Dinleyici EÇ, Kara A. Antibiotic associated diarrhea in outpatient pediatric antibiotic therapy. BMC Pediatr. 2023 Mar 18;23(1):121. doi: 10.1186/s12887-023-03939-w. PMID: 36932373; PMCID: PMC10024443.

4. McFarland L.V. (2006) Metaanalysis of probiotics for the prevention of antibiotic associated diarrhea and the treatment of Clostridium difficile disease Am J Gastroenterol 101: 812–822 [PubMed] [Google Scholar] [Ref list]

 

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